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Rules for biocatalyst and reaction engineering to implement effective, NAD(P)H-dependent, whole cell bioreductions

Access to chiral alcohols of high optical purity is today frequently provided by the enzymatic reduction of precursor ketones. However, bioreductions are complicated by the need for reducing equivalents in the form of NAD(P)H. The high price and molecular weight of NAD(P)H necessitate in situ recycl...

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Detalles Bibliográficos
Autores principales: Kratzer, Regina, Woodley, John M., Nidetzky, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414839/
https://www.ncbi.nlm.nih.gov/pubmed/26343336
http://dx.doi.org/10.1016/j.biotechadv.2015.08.006