T cell therapy targeting a public neoantigen in microsatellite instable colon cancer reduces in vivo tumor growth

T-cell receptor (TCR) transfer is an attractive strategy to increase the number of cancer-specific T cells in adoptive cell therapy. However, recent clinical and pre-clinical findings indicate that careful consideration of the target antigen is required to limit the risk of off-target toxicity. Dire...

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Detalles Bibliográficos
Autores principales: Inderberg, Else M., Wälchli, Sébastien, Myhre, Marit R., Trachsel, Sissel, Almåsbak, Hilde, Kvalheim, Gunnar, Gaudernack, Gustav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414866/
https://www.ncbi.nlm.nih.gov/pubmed/28507809
http://dx.doi.org/10.1080/2162402X.2017.1302631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414866/
https://www.ncbi.nlm.nih.gov/pubmed/28507809
http://dx.doi.org/10.1080/2162402X.2017.1302631

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