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T cell therapy targeting a public neoantigen in microsatellite instable colon cancer reduces in vivo tumor growth
T-cell receptor (TCR) transfer is an attractive strategy to increase the number of cancer-specific T cells in adoptive cell therapy. However, recent clinical and pre-clinical findings indicate that careful consideration of the target antigen is required to limit the risk of off-target toxicity. Dire...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414866/ https://www.ncbi.nlm.nih.gov/pubmed/28507809 http://dx.doi.org/10.1080/2162402X.2017.1302631 |