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Calreticulin promotes immunity and type I interferon-dependent survival in mice with acute myeloid leukemia

Exposure of cancer cells to particular chemotherapeutic agents or γ-irradiation induces a form of cell death that stimulates an immune response in mice. This “immunogenic cell death” requires calreticulin (CRT) translocation to the plasma membrane, which has been shown to promote cancer cell phagocy...

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Detalles Bibliográficos
Autores principales: Chen, Xiufen, Fosco, Dominick, Kline, Douglas E., Kline, Justin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414882/
https://www.ncbi.nlm.nih.gov/pubmed/28507789
http://dx.doi.org/10.1080/2162402X.2016.1278332