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Calreticulin promotes immunity and type I interferon-dependent survival in mice with acute myeloid leukemia
Exposure of cancer cells to particular chemotherapeutic agents or γ-irradiation induces a form of cell death that stimulates an immune response in mice. This “immunogenic cell death” requires calreticulin (CRT) translocation to the plasma membrane, which has been shown to promote cancer cell phagocy...
Autores principales: | Chen, Xiufen, Fosco, Dominick, Kline, Douglas E., Kline, Justin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414882/ https://www.ncbi.nlm.nih.gov/pubmed/28507789 http://dx.doi.org/10.1080/2162402X.2016.1278332 |
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