Quantitative longitudinal imaging of activated microglia as a marker of inflammation in the pilocarpine rat model of epilepsy using [(11)C]-(R)-PK11195 PET and MRI

Inflammation may play a role in the development of epilepsy after brain insults. [(11)C]-(R)-PK11195 binds to TSPO, expressed by activated microglia. We quantified [(11)C]-(R)-PK11195 binding during epileptogenesis after pilocarpine-induced status epilepticus (SE), a model of temporal lobe epilepsy....

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Detalles Bibliográficos
Autores principales: Yankam Njiwa, J, Costes, N, Bouillot, C, Bouvard, S, Fieux, S, Becker, G, Levigoureux, E, Kocevar, G, Stamile, C, Langlois, JB, Bolbos, R, Bonnet, C, Bezin, L, Zimmer, L, Hammers, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414902/
https://www.ncbi.nlm.nih.gov/pubmed/27381824
http://dx.doi.org/10.1177/0271678X16653615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414902/
https://www.ncbi.nlm.nih.gov/pubmed/27381824
http://dx.doi.org/10.1177/0271678X16653615

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