PKBγ/AKT3 loss-of-function causes learning and memory deficits and deregulation of AKT/mTORC2 signaling: Relevance for schizophrenia

Psychiatric genetic studies have identified genome-wide significant loci for schizophrenia. The AKT3/1q44 locus is a principal risk region and gene-network analyses identify AKT3 polymorphisms as a constituent of several neurobiological pathways relevant to psychiatric risk; the neurobiological mech...

Descripción completa

Detalles Bibliográficos
Autores principales: Howell, Kristy R., Floyd, Kirsten, Law, Amanda J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414975/
https://www.ncbi.nlm.nih.gov/pubmed/28467426
http://dx.doi.org/10.1371/journal.pone.0175993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414975/
https://www.ncbi.nlm.nih.gov/pubmed/28467426
http://dx.doi.org/10.1371/journal.pone.0175993

Ejemplares similares