Smek promotes corticogenesis through regulating Mbd3’s stability and Mbd3/NuRD complex recruitment to genes associated with neurogenesis

The fate of neural progenitor cells (NPCs) during corticogenesis is determined by a complex interplay of genetic or epigenetic components, but the underlying mechanism is incompletely understood. Here, we demonstrate that Suppressor of Mek null (Smek) interact with methyl-CpG–binding domain 3 (Mbd3)...

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Detalles Bibliográficos
Autores principales: Moon, Byoung-San, Yun, Hyung-Mun, Chang, Wen-Hsuan, Steele, Bradford H., Cai, Mingyang, Choi, Si Ho, Lu, Wange
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414985/
https://www.ncbi.nlm.nih.gov/pubmed/28467410
http://dx.doi.org/10.1371/journal.pbio.2001220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414985/
https://www.ncbi.nlm.nih.gov/pubmed/28467410
http://dx.doi.org/10.1371/journal.pbio.2001220

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