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“Wait anaphase” signals are not confined to the mitotic spindle

The spindle assembly checkpoint ensures the faithful inheritance of chromosomes by arresting mitotic progression in the presence of kinetochores that are not attached to spindle microtubules. This is achieved through inhibition of the anaphase-promoting complex/cyclosome by a kinetochore-derived “wa...

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Detalles Bibliográficos
Autores principales: Heasley, Lydia R., Markus, Steven M., DeLuca, Jennifer G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415015/
https://www.ncbi.nlm.nih.gov/pubmed/28298492
http://dx.doi.org/10.1091/mbc.E17-01-0036