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TGF-β triggers rapid fibrillogenesis via a novel TβRII-dependent fibronectin-trafficking mechanism

Fibronectin (FN) is a critical regulator of extracellular matrix (ECM) remodeling through its availability and stepwise polymerization for fibrillogenesis. Availability of FN is regulated by its synthesis and turnover, and fibrillogenesis is a multistep, integrin-dependent process essential for cell...

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Detalles Bibliográficos
Autores principales: Varadaraj, Archana, Jenkins, Laura M., Singh, Priyanka, Chanda, Anindya, Snider, John, Lee, N. Y., Amsalem-Zafran, Ayelet R., Ehrlich, Marcelo, Henis, Yoav I., Mythreye, Karthikeyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415016/
https://www.ncbi.nlm.nih.gov/pubmed/28298487
http://dx.doi.org/10.1091/mbc.E16-08-0601