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TGF-β triggers rapid fibrillogenesis via a novel TβRII-dependent fibronectin-trafficking mechanism
Fibronectin (FN) is a critical regulator of extracellular matrix (ECM) remodeling through its availability and stepwise polymerization for fibrillogenesis. Availability of FN is regulated by its synthesis and turnover, and fibrillogenesis is a multistep, integrin-dependent process essential for cell...
Autores principales: | Varadaraj, Archana, Jenkins, Laura M., Singh, Priyanka, Chanda, Anindya, Snider, John, Lee, N. Y., Amsalem-Zafran, Ayelet R., Ehrlich, Marcelo, Henis, Yoav I., Mythreye, Karthikeyan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415016/ https://www.ncbi.nlm.nih.gov/pubmed/28298487 http://dx.doi.org/10.1091/mbc.E16-08-0601 |
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