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CYK-4 regulates Rac, but not Rho, during cytokinesis

Cytokinesis is driven by constriction of an actomyosin contractile ring that is controlled by Rho-family small GTPases. Rho, activated by the guanine-nucleotide exchange factor ECT-2, is upstream of both myosin-II activation and diaphanous formin-mediated filamentous actin (f-actin) assembly, which...

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Detalles Bibliográficos
Autores principales: Zhuravlev, Yelena, Hirsch, Sophia M., Jordan, Shawn N., Dumont, Julien, Shirasu-Hiza, Mimi, Canman, Julie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415020/
https://www.ncbi.nlm.nih.gov/pubmed/28298491
http://dx.doi.org/10.1091/mbc.E17-01-0020