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Deubiquitinating enzymes Ubp2 and Ubp15 regulate endocytosis by limiting ubiquitination and degradation of ARTs

Endocytic down-regulation of cell-surface proteins is a fundamental cellular process for cell survival and adaptation to environmental stimuli. Ubiquitination of cargo proteins serves as the sorting signal for downstream trafficking and relies on the arrestin-related trafficking adaptor (ART)-Rsp5 u...

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Detalles Bibliográficos
Autores principales: Ho, Hsuan-Chung, MacGurn, Jason A., Emr, Scott D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415021/
https://www.ncbi.nlm.nih.gov/pubmed/28298493
http://dx.doi.org/10.1091/mbc.E17-01-0008