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The anti-microbial peptide TP359 attenuates inflammation in human lung cells infected with Pseudomonas aeruginosa via TLR5 and MAPK pathways

Pseudomonas aeruginosa infection induces vigorous inflammatory mediators secreted by epithelial cells, which do not necessarily eradicate the pathogen. Nonetheless, it reduces lung function due to significant airway damage, most importantly in cystic fibrosis patients. Recently, we published that TP...

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Detalles Bibliográficos
Autores principales: Dosunmu, Ejovwoke F., Emeh, Robert O., Dixit, Saurabh, Bakeer, Mona K., Coats, Mamie T., Owen, Donald R., Pillai, Shreekumar R., Singh, Shree R., Dennis, Vida A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415104/
https://www.ncbi.nlm.nih.gov/pubmed/28467446
http://dx.doi.org/10.1371/journal.pone.0176640