Dpb11 may function with RPA and DNA to initiate DNA replication

Dpb11 is required for the initiation of DNA replication in budding yeast. We found that Dpb11 binds tightly to single-stranded DNA (ssDNA) or branched DNA structures, while its human homolog, TopBP1, binds tightly to branched-DNA structures. We also found that Dpb11 binds stably to CDK-phosphorylate...

Descripción completa

Detalles Bibliográficos
Autores principales: Bruck, Irina, Dhingra, Nalini, Martinez, Matthew P., Kaplan, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415106/
https://www.ncbi.nlm.nih.gov/pubmed/28467467
http://dx.doi.org/10.1371/journal.pone.0177147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415106/
https://www.ncbi.nlm.nih.gov/pubmed/28467467
http://dx.doi.org/10.1371/journal.pone.0177147

Ejemplares similares