Cargando…

Dpb11 may function with RPA and DNA to initiate DNA replication

Dpb11 is required for the initiation of DNA replication in budding yeast. We found that Dpb11 binds tightly to single-stranded DNA (ssDNA) or branched DNA structures, while its human homolog, TopBP1, binds tightly to branched-DNA structures. We also found that Dpb11 binds stably to CDK-phosphorylate...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bruck, Irina, Dhingra, Nalini, Martinez, Matthew P., Kaplan, Daniel L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415106/ https://www.ncbi.nlm.nih.gov/pubmed/28467467 http://dx.doi.org/10.1371/journal.pone.0177147

Ejemplares similares

Distinct RPA functions promote eukaryotic DNA replication initiation and elongation
por: Pike, Alexandra M, et al.
Publicado: (2023)

Eukaryotic Replicative Helicase Subunit Interaction with DNA and Its Role in DNA Replication
por: Martinez, Matthew P., et al.
Publicado: (2017)

WASp modulates RPA function on single-stranded DNA in response to replication stress and DNA damage
por: Han, Seong-Su, et al.
Publicado: (2022)

Proper RPA acetylation promotes accurate DNA replication and repair
por: Gan, Xiaoli, et al.
Publicado: (2023)

A cell cycle-regulated Slx4–Dpb11 complex promotes the resolution of DNA repair intermediates linked to stalled replication
por: Gritenaite, Dalia, et al.
Publicado: (2014)

A dynamic model for replication protein A (RPA) function in DNA processing pathways
por: Fanning, Ellen, et al.
Publicado: (2006)

TopBP1/Dpb11 binds DNA anaphase bridges to prevent genome instability
por: Germann, Susanne M., et al.
Publicado: (2014)

Mutations in the Non-Catalytic Subunit Dpb2 of DNA Polymerase Epsilon Affect the Nrm1 Branch of the DNA Replication Checkpoint
por: Dmowski, Michał, et al.
Publicado: (2017)

Role of the Polymerase ϵ sub-unit DPB2 in DNA replication, cell cycle regulation and DNA damage response in Arabidopsis
por: Pedroza-Garcia, José Antonio, et al.
Publicado: (2016)

A cell cycle-independent mode of the Rad9-Dpb11 interaction is induced by DNA damage
por: di Cicco, Giulia, et al.
Publicado: (2017)

Evidence for direct contact between the RPA3 subunit of the human replication protein A and single-stranded DNA
por: Salas, Tonatiuh Romero, et al.
Publicado: (2009)

Typhoid toxin exhausts the RPA response to DNA replication stress driving senescence and Salmonella infection
por: Ibler, Angela E. M., et al.
Publicado: (2019)

HARP preferentially co-purifies with RPA bound to DNA-PK and blocks RPA phosphorylation
por: Quan, Jinhua, et al.
Publicado: (2014)

Targeting of the Fun30 nucleosome remodeller by the Dpb11 scaffold facilitates cell cycle-regulated DNA end resection
por: Bantele, Susanne CS, et al.
Publicado: (2017)

Phosphorylated RPA recruits PALB2 to stalled DNA replication forks to facilitate fork recovery
por: Murphy, Anar K., et al.
Publicado: (2014)

Diverse roles of Dpb2, the non-catalytic subunit of DNA polymerase ε
por: Dmowski, Michał, et al.
Publicado: (2017)

Mechanochemical regulations of RPA's binding to ssDNA
por: Chen, Jin, et al.
Publicado: (2015)

Replication Protein A (RPA) Hampers the Processive Action of APOBEC3G Cytosine Deaminase on Single-Stranded DNA
por: Lada, Artem G., et al.
Publicado: (2011)

RPA activates the XPF‐ERCC1 endonuclease to initiate processing of DNA interstrand crosslinks
por: Abdullah, Ummi B, et al.
Publicado: (2017)

Origin DNA Melting—An Essential Process with Divergent Mechanisms
por: Martinez, Matthew P., et al.
Publicado: (2017)

RPA shields inherited DNA lesions for post-mitotic DNA synthesis
por: Lezaja, Aleksandra, et al.
Publicado: (2021)

Cervical cancer isolate PT3, super-permissive for adeno-associated virus replication, over-expresses DNA polymerase δ, PCNA, RFC and RPA
por: Kang, Bum Yong, et al.
Publicado: (2009)

Dual functions for the ssDNA-binding protein RPA in meiotic recombination
por: Shi, Baolu, et al.
Publicado: (2019)

Distinct roles for DNA-PK, ATM and ATR in RPA phosphorylation and checkpoint activation in response to replication stress
por: Liu, Shengqin, et al.
Publicado: (2012)

The Bloom syndrome complex senses RPA-coated single-stranded DNA to restart stalled replication forks
por: Shorrocks, Ann-Marie K., et al.
Publicado: (2021)

PHOSPHORYLATION-DEPENDENT ASSOCIATION OF WRN WITH RPA IS REQUIRED FOR RECOVERY OF REPLICATION FORKS STALLED AT SECONDARY DNA STRUCTURES
por: Noto, Alessandro, et al.
Publicado: (2023)

DPB-NBFnet: Using neural Bellman-Ford networks to predict DNA-protein binding
por: Li, Jing, et al.
Publicado: (2022)

Force regulated dynamics of RPA on a DNA fork
por: Kemmerich, Felix E., et al.
Publicado: (2016)

Dynamics and Selective Remodeling of the DNA Binding Domains of RPA
por: Pokhrel, Nilisha, et al.
Publicado: (2019)

Radioresistance, DNA Damage and DNA Repair in Cells With Moderate Overexpression of RPA1
por: Velegzhaninov, Ilya O., et al.
Publicado: (2020)

Deciphering the mechanism of processive ssDNA digestion by the Dna2-RPA ensemble
por: Shen, Jiangchuan, et al.
Publicado: (2022)

A naturally occurring human RPA subunit homolog does not support DNA replication or cell-cycle progression
por: Haring, Stuart J., et al.
Publicado: (2010)

Extensive RPA2 hyperphosphorylation promotes apoptosis in response to DNA replication stress in CHK1 inhibited cells
por: Zuazua-Villar, Pedro, et al.
Publicado: (2015)

Rtt105 regulates RPA function by configurationally stapling the flexible domains
por: Kuppa, Sahiti, et al.
Publicado: (2022)

RPA homologs and ssDNA processing during meiotic recombination
por: Ribeiro, Jonathan, et al.
Publicado: (2015)

Architecture and ssDNA interaction of the Timeless-Tipin-RPA complex
por: Witosch, Justine, et al.
Publicado: (2014)

Dna2 nuclease-helicase structure, mechanism and regulation by Rpa
por: Zhou, Chun, et al.
Publicado: (2015)

A DNA Barcode-Based RPA Assay (BAR-RPA) for Rapid Identification of the Dry Root of Ficus hirta (Wuzhimaotao)
por: Tian, Enwei, et al.
Publicado: (2017)

Dpb11, the budding yeast homolog of TopBP1, functions with the checkpoint clamp in recombination repair
por: Ogiwara, Hideaki, et al.
Publicado: (2006)

Viral Interference with DNA Repair by Targeting of the Single-Stranded DNA Binding Protein RPA
por: Banerjee, Pubali, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_6s2abkne0bdn8ijhu4oenneuak