Zebrafish GDNF and its co-receptor GFRα1 activate the human RET receptor and promote the survival of dopaminergic neurons in vitro

Glial cell line-derived neurotrophic factor (GDNF) is a ligand that activates, through co-receptor GDNF family receptor alpha-1 (GFRα1) and receptor tyrosine kinase “RET”, several signaling pathways crucial in the development and sustainment of multiple neuronal populations. We decided to study whet...

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Detalles Bibliográficos
Autores principales: Saarenpää, Tuulia, Kogan, Konstantin, Sidorova, Yulia, Mahato, Arun Kumar, Tascón, Igor, Kaljunen, Heidi, Yu, Liying, Kallijärvi, Jukka, Jurvansuu, Jaana, Saarma, Mart, Goldman, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415192/
https://www.ncbi.nlm.nih.gov/pubmed/28467503
http://dx.doi.org/10.1371/journal.pone.0176166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415192/
https://www.ncbi.nlm.nih.gov/pubmed/28467503
http://dx.doi.org/10.1371/journal.pone.0176166

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