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Chromatin-modifying agents convert fibroblasts to OCT4+ and VEGFR-2+ capillary tube-forming cells

RATIONALE: The human epigenome is plastic. The goal of this study was to address if fibroblast cells can be epigenetically modified to promote neovessel formation. METHODS AND RESULTS: Here, we used highly abundant human adult dermal fibroblast cells (hADFCs) that were treated with the chromatin-mod...

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Detalles Bibliográficos
Autores principales: Wary, Anita, Wary, Neil, Baruah, Jugajyoti, Mastej, Victoria, Wary, Kishore K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415225/
https://www.ncbi.nlm.nih.gov/pubmed/28467484
http://dx.doi.org/10.1371/journal.pone.0176496