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Viral Vector-Based Innovative Approaches to Directly Abolishing Tumorigenic Pluripotent Stem Cells for Safer Regenerative Medicine

Human pluripotent stem cells (hPSCs) are a promising source of regenerative material for clinical applications. However, hPSC transplant therapies pose the risk of teratoma formation and malignant transformation of undifferentiated remnants. These problems underscore the importance of developing tec...

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Detalles Bibliográficos
Autores principales: Mitsui, Kaoru, Ide, Kanako, Takahashi, Tomoyuki, Kosai, Ken-ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415317/
https://www.ncbi.nlm.nih.gov/pubmed/28480304
http://dx.doi.org/10.1016/j.omtm.2017.03.002