Cargando…

Humanized Mice with Subcutaneous Human Solid Tumors for Immune Response Analysis of Vaccinia Virus-Mediated Oncolysis

Oncolytic vaccinia virus (VACV) therapy is an alternative cancer treatment modality that mediates targeted tumor destruction through a tumor-selective replication and an induction of anti-tumor immunity. We developed a humanized tumor mouse model with subcutaneous human tumors to analyze the interac...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsoneva, Desislava, Minev, Boris, Frentzen, Alexa, Zhang, Qian, Wege, Anja K., Szalay, Aladar A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415323/
https://www.ncbi.nlm.nih.gov/pubmed/28480327
http://dx.doi.org/10.1016/j.omto.2017.03.001