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Humanized Mice with Subcutaneous Human Solid Tumors for Immune Response Analysis of Vaccinia Virus-Mediated Oncolysis
Oncolytic vaccinia virus (VACV) therapy is an alternative cancer treatment modality that mediates targeted tumor destruction through a tumor-selective replication and an induction of anti-tumor immunity. We developed a humanized tumor mouse model with subcutaneous human tumors to analyze the interac...
Autores principales: | Tsoneva, Desislava, Minev, Boris, Frentzen, Alexa, Zhang, Qian, Wege, Anja K., Szalay, Aladar A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415323/ https://www.ncbi.nlm.nih.gov/pubmed/28480327 http://dx.doi.org/10.1016/j.omto.2017.03.001 |
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