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Spatially and Temporally Regulated NRF2 Gene Therapy Using Mcp-1 Promoter in Retinal Ganglion Cell Injury

Retinal ganglion cell degeneration triggered by axonal injury is believed to underlie many ocular diseases, including glaucoma and optic neuritis. In these diseases, retinal ganglion cells are affected unevenly, both spatially and temporally, such that healthy and unhealthy cells coexist in differen...

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Detalles Bibliográficos
Autores principales: Fujita, Kosuke, Nishiguchi, Koji M., Shiga, Yukihiro, Nakazawa, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415330/
https://www.ncbi.nlm.nih.gov/pubmed/28480312
http://dx.doi.org/10.1016/j.omtm.2017.04.003