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The long noncoding RNA SPRIGHTLY acts as an intranuclear organizing hub for pre-mRNA molecules

Molecular mechanisms by which long noncoding RNA (lncRNA) molecules may influence cancerous condition are poorly understood. The aberrant expression of SPRIGHTLY lncRNA, encoded within the drosophila gene homolog Sprouty-4 intron, is correlated with a variety of cancers, including human melanomas. W...

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Detalles Bibliográficos
Autores principales: Lee, Bongyong, Sahoo, Anupama, Marchica, John, Holzhauser, Erwin, Chen, Xiaoli, Li, Jian-Liang, Seki, Tatsuya, Govindarajan, Subramaniam Shyamala, Markey, Fatu Badiane, Batish, Mona, Lokhande, Sonali J., Zhang, Shaojie, Ray, Animesh, Perera, Ranjan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415337/
https://www.ncbi.nlm.nih.gov/pubmed/28508063
http://dx.doi.org/10.1126/sciadv.1602505