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Regulation of localization and function of the transcriptional co-activator YAP by angiomotin

The Hippo-YAP pathway is a central regulator of cell contact inhibition, proliferation and death. There are conflicting reports regarding the role of Angiomotin (Amot) in regulating this pathway. While some studies suggest a YAP-inhibitory function other studies indicate Amot is required for YAP act...

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Detalles Bibliográficos
Autores principales: Moleirinho, Susana, Hoxha, Sany, Mandati, Vinay, Curtale, Graziella, Troutman, Scott, Ehmer, Ursula, Kissil, Joseph L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415356/
https://www.ncbi.nlm.nih.gov/pubmed/28464980
http://dx.doi.org/10.7554/eLife.23966