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HPV16-E7-Specific Activated CD8 T Cells in E7 Transgenic Skin and Skin Grafts

Human papillomavirus (HPV) 16 E7 (E7) protein expression in skin promotes epithelial hyperproliferation and transformation to malignancy. Grafts of murine skin expressing E7 protein as a transgene in keratinocytes are not rejected from immunocompetent recipients, whereas grafts expressing ovalbumin...

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Detalles Bibliográficos
Autores principales: Jazayeri, Seyed Davoud, Kuo, Paula T., Leggatt, Graham Robert, Frazer, Ian H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415560/
https://www.ncbi.nlm.nih.gov/pubmed/28523003
http://dx.doi.org/10.3389/fimmu.2017.00524