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The KEAP1–NRF2 System in Cancer

Cancer cells first adapt to the microenvironment and then propagate. Mutations in tumor suppressor genes or oncogenes are frequently found in cancer cells. Comprehensive genomic analyses have identified somatic mutations and other alterations in the KEAP1 or NRF2 genes and in well-known tumor suppre...

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Detalles Bibliográficos
Autores principales: Taguchi, Keiko, Yamamoto, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415577/
https://www.ncbi.nlm.nih.gov/pubmed/28523248
http://dx.doi.org/10.3389/fonc.2017.00085