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ZNF750 is a lineage-specific tumour suppressor in squamous cell carcinoma

ZNF750 controls epithelial homeostasis by regulating epidermal-differentiation genes, a role underscored by its pathogenic mutations in esophageal squamous cell cancers (SCCs). However, the precise role of ZNF750 in SCC cell biology remains unclear. In this study, we report that ZNF750 is exclusivel...

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Detalles Bibliográficos
Autores principales: Hazawa, M, Lin, D-C, Handral, H, Xu, L, Chen, Y, Jiang, Y-Y, Mayakonda, A, Ding, L-W, Meng, X, Sharma, A, Samuel, S, Movahednia, M M, Wong, R W, Yang, H, Tong, C, Koeffler, H P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415641/
https://www.ncbi.nlm.nih.gov/pubmed/27819679
http://dx.doi.org/10.1038/onc.2016.377