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Proteomic anaysis of aged microglia: shifts in transcription, bioenergetics, and nutrient response

BACKGROUND: Age is the primary risk factor for many diseases. As such, age is a critical co-factor for examination in order to understand the progression and potential intervention in disease progression. Studies examining both the phenotype and transcriptome of aged microglia demonstrated a propens...

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Detalles Bibliográficos
Autores principales: Flowers, Antwoine, Bell-Temin, Harris, Jalloh, Ahmad, Stevens, Stanley M., Bickford, Paula C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415769/
https://www.ncbi.nlm.nih.gov/pubmed/28468668
http://dx.doi.org/10.1186/s12974-017-0840-7