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IgG silencing induces apoptosis and suppresses proliferation, migration and invasion in LNCaP prostate cancer cells

Immunoglobulin G (IgG) has been implicated in the progression of various cancers. This study explored the role of IgG in the proliferation, apoptosis, cell cycle and in vitro invasive properties of LNCaP prostate cancer cells. We used IGHG1 small interfering RNA to silence IgG1 expression in LNCaP c...

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Detalles Bibliográficos
Autores principales: Xu, Yawen, Chen, Binshen, Zheng, Shaobo, Wen, Yong, Xu, Abai, Xu, Kai, Li, Bingkun, Liu, Chunxiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415809/
https://www.ncbi.nlm.nih.gov/pubmed/28536629
http://dx.doi.org/10.1186/s11658-016-0029-6