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KRAS mutation analysis of single circulating tumor cells from patients with metastatic colorectal cancer

BACKGROUND: The molecular profiles of tumors may inform the selection of appropriate targeted therapies. Circulating tumor cells (CTCs) reflect the real-time status of tumor genotypes. CTCs exhibit high genetic heterogeneity within a patient; accordingly, the analysis of individual CTCs, including t...

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Detalles Bibliográficos
Autores principales: Kondo, Yuurin, Hayashi, Kazuhiko, Kawakami, Kazuyuki, Miwa, Yukari, Hayashi, Hiroshi, Yamamoto, Masakazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415811/
https://www.ncbi.nlm.nih.gov/pubmed/28468669
http://dx.doi.org/10.1186/s12885-017-3305-6