Female gonadal hormone effects on microglial activation and functional outcomes in a mouse model of moderate traumatic brain injury

AIM: To address the hypothesis that young, gonad-intact female mice have improved long-term recovery associated with decreased neuroinflammation compared to male mice. METHODS: Eight to ten week-old male, female, and ovariectomized (OVX) mice underwent closed cranial impact. Gonad-intact female mice...

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Detalles Bibliográficos
Autores principales: Umeano, Odera, Wang, Haichen, Dawson, Hana, Lei, Beilei, Umeano, Afoma, Kernagis, Dawn, James, Michael L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Basic Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415850/
https://www.ncbi.nlm.nih.gov/pubmed/28529912
http://dx.doi.org/10.5492/wjccm.v6.i2.107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415850/
https://www.ncbi.nlm.nih.gov/pubmed/28529912
http://dx.doi.org/10.5492/wjccm.v6.i2.107

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