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Female gonadal hormone effects on microglial activation and functional outcomes in a mouse model of moderate traumatic brain injury
AIM: To address the hypothesis that young, gonad-intact female mice have improved long-term recovery associated with decreased neuroinflammation compared to male mice. METHODS: Eight to ten week-old male, female, and ovariectomized (OVX) mice underwent closed cranial impact. Gonad-intact female mice...
Autores principales: | Umeano, Odera, Wang, Haichen, Dawson, Hana, Lei, Beilei, Umeano, Afoma, Kernagis, Dawn, James, Michael L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415850/ https://www.ncbi.nlm.nih.gov/pubmed/28529912 http://dx.doi.org/10.5492/wjccm.v6.i2.107 |
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