Enhancing Accuracy in Molecular Weight Determination of Highly Heterogeneously Glycosylated Proteins by Native Tandem Mass Spectrometry

[Image: see text] The determination of molecular weights (MWs) of heavily glycosylated proteins is seriously hampered by the physicochemical characteristics and heterogeneity of the attached carbohydrates. Glycosylation impacts protein migration during sodium dodecyl sulfate (SDS)-polyacrylamide gel...

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Detalles Bibliográficos
Autores principales: Wang, Guanbo, de Jong, Rob N., van den Bremer, Ewald T. J., Parren, Paul W. H. I., Heck, Albert J. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415875/
https://www.ncbi.nlm.nih.gov/pubmed/28383250
http://dx.doi.org/10.1021/acs.analchem.6b05129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415875/
https://www.ncbi.nlm.nih.gov/pubmed/28383250
http://dx.doi.org/10.1021/acs.analchem.6b05129

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