Cargando…

Enhancing Accuracy in Molecular Weight Determination of Highly Heterogeneously Glycosylated Proteins by Native Tandem Mass Spectrometry

[Image: see text] The determination of molecular weights (MWs) of heavily glycosylated proteins is seriously hampered by the physicochemical characteristics and heterogeneity of the attached carbohydrates. Glycosylation impacts protein migration during sodium dodecyl sulfate (SDS)-polyacrylamide gel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Guanbo, de Jong, Rob N., van den Bremer, Ewald T. J., Parren, Paul W. H. I., Heck, Albert J. R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2017
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415875/ https://www.ncbi.nlm.nih.gov/pubmed/28383250 http://dx.doi.org/10.1021/acs.analchem.6b05129

Ejemplares similares

In-depth qualitative and quantitative analysis of composite glycosylation profiles and other micro-heterogeneity on intact monoclonal antibodies by high-resolution native mass spectrometry using a modified Orbitrap
por: Rosati, Sara, et al.
Publicado: (2013)

High-Resolution Native Mass Spectrometry
por: Tamara, Sem, et al.
Publicado: (2021)

Native Mass Spectrometry: What is in the Name?
por: Leney, Aneika C., et al.
Publicado: (2016)

Mutation of Y407 in the CH3 domain dramatically alters glycosylation and structure of human IgG
por: Rose, Rebecca J., et al.
Publicado: (2013)

Examining the Heterogeneous Genome Content of Multipartite Viruses BMV and CCMV by Native Mass Spectrometry
por: van de Waterbeemd, Michiel, et al.
Publicado: (2016)

Comparative Analysis of Antibodies and Heavily Glycosylated Macromolecular Immune Complexes by Size-Exclusion Chromatography Multi-Angle Light Scattering, Native Charge Detection Mass Spectrometry, and Mass Photometry
por: den Boer, Maurits A., et al.
Publicado: (2021)

Dissecting the structural heterogeneity of proteins by native mass spectrometry
por: Reid, Deseree J., et al.
Publicado: (2023)

Analyzing Protein Micro-Heterogeneity in Chicken Ovalbumin by High-Resolution Native Mass Spectrometry Exposes Qualitatively and Semi-Quantitatively 59 Proteoforms
por: Yang, Yang, et al.
Publicado: (2013)

Resolving the micro-heterogeneity and structural integrity of monoclonal antibodies by hybrid mass spectrometric approaches
por: Yang, Yang, et al.
Publicado: (2017)

Characterization of protein N-glycosylation by tandem mass spectrometry using complementary fragmentation techniques
por: Ford, Kristina L., et al.
Publicado: (2015)

Parsimonious Charge Deconvolution for Native Mass Spectrometry
por: Bern, Marshall, et al.
Publicado: (2018)

Comparative Glycopeptide Analysis for Protein Glycosylation by Liquid Chromatography and Tandem Mass Spectrometry: Variation in Glycosylation Patterns of Site-Directed Mutagenized Glycoprotein
por: Hahm, Young Hye, et al.
Publicado: (2018)

Charting the Proteoform Landscape of Serum Proteins in Individual Donors by High-Resolution Native Mass Spectrometry
por: Cramer, Dario A. T., et al.
Publicado: (2022)

Direct Monitoring of Protein O-GlcNAcylation by High-Resolution Native Mass Spectrometry
por: Leney, Aneika C., et al.
Publicado: (2017)

Meta-heterogeneity: Evaluating and Describing the Diversity in Glycosylation Between Sites on the Same Glycoprotein
por: Čaval, Tomislav, et al.
Publicado: (2020)

Expanding the mass range for UVPD-based native top-down mass spectrometry
por: Greisch, Jean-François, et al.
Publicado: (2019)

Identification of pathogens from native urine samples by MALDI-TOF/TOF tandem mass spectrometry
por: Oros, Damir, et al.
Publicado: (2020)

Discrepancies between High-Resolution Native and Glycopeptide-Centric Mass Spectrometric Approaches: A Case Study into the Glycosylation of Erythropoietin Variants
por: Čaval, Tomislav, et al.
Publicado: (2021)

Qualitative and Quantitative Analysis of C-glycosyl-flavones of Iris lactea Leaves by Liquid Chromatography/Tandem Mass Spectrometry
por: Chen, Dan, et al.
Publicado: (2018)

Stochastic palmitoylation of accessible cysteines in membrane proteins revealed by native mass spectrometry
por: Rodenburg, Remco N. P., et al.
Publicado: (2017)

Site-Specific N-Linked Glycosylation Analysis of Human Carcinoembryonic Antigen by Sheathless Capillary Electrophoresis–Tandem Mass Spectrometry
por: Pont, Laura, et al.
Publicado: (2021)

Native mass spectrometry combined with enzymatic dissection unravels glycoform heterogeneity of biopharmaceuticals
por: Wohlschlager, Therese, et al.
Publicado: (2018)

Relating glycoprotein structural heterogeneity to function – insights from native mass spectrometry
por: Struwe, Weston B, et al.
Publicado: (2019)

Probing Polyester Branching by Hybrid Trapped Ion-Mobility Spectrometry–Tandem Mass Spectrometry
por: Voeten, Robert L. C., et al.
Publicado: (2021)

Novel Glycosylation Sites Localized in Campylobacter jejuni Flagellin FlaA by Liquid Chromatography Electron Capture Dissociation Tandem Mass Spectrometry
por: Zampronio, Cleidiane G., et al.
Publicado: (2010)

Progressive search in tandem mass spectrometry
por: Joh, Yoonsung, et al.
Publicado: (2023)

Two-dimensional mass spectrometry: new perspectives for tandem mass spectrometry
por: van Agthoven, Maria A., et al.
Publicado: (2019)

Protein Glycosylation Investigated by Mass Spectrometry: An Overview
por: Illiano, Anna, et al.
Publicado: (2020)

A mass accuracy sensitive probability based scoring algorithm for database searching of tandem mass spectrometry data
por: Xu, Hua, et al.
Publicado: (2007)

Stochastic assembly of biomacromolecular complexes: impact and implications on charge interpretation in native mass spectrometry
por: Yin, Victor, et al.
Publicado: (2023)

Accuracy evaluation of automated electrochemiluminescence immunoassay for everolimus and sirolimus compared to liquid chromatography‐tandem mass spectrometry
por: Lee, Eun Jin, et al.
Publicado: (2019)

Generating Informative Sequence Tags from Antigen-Binding Regions of Heavily Glycosylated IgA1 Antibodies by Native Top-Down Electron Capture Dissociation
por: Greisch, Jean-Francois, et al.
Publicado: (2021)

Developments in tandem ion mobility mass spectrometry
por: Eldrid, Charles, et al.
Publicado: (2020)

In Search of Disentanglement in Tandem Mass Spectrometry Datasets
por: Abram, Krzysztof Jan, et al.
Publicado: (2023)

Liquid chromatography–tandem mass spectrometry for clinical diagnostics
por: Thomas, Stefani N., et al.
Publicado: (2022)

Mass spectrometry for serine ADP-ribosylation? Think o-glycosylation!
por: Bonfiglio, Juan J., et al.
Publicado: (2017)

Coupling Anion Exchange Chromatography with Native Mass Spectrometry for Charge Heterogeneity Characterization of Monoclonal Antibodies
por: Liu, Anita P., et al.
Publicado: (2022)

Glycosylation of viral surface proteins probed by mass spectrometry
por: Hargett, Audra A, et al.
Publicado: (2019)

Simultaneous Method for Selected PBDEs and HBCDDs in Foodstuffs Using Gas Chromatography—Tandem Mass Spectrometry and Liquid Chromatography—Tandem Mass Spectrometry
por: Lipičar, Eva, et al.
Publicado: (2022)

BLINK enables ultrafast tandem mass spectrometry cosine similarity scoring
por: Harwood, Thomas V., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_jesogqn2h5687bt16fdibur910