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Inhibition of Mef2a Enhances Neovascularization via Post-transcriptional Regulation of 14q32 MicroRNAs miR-329 and miR-494

Improving the efficacy of neovascularization is a promising strategy to restore perfusion of ischemic tissues in patients with peripheral arterial disease. The 14q32 microRNA cluster is highly involved in neovascularization. The Mef2a transcription factor has been shown to induce transcription of th...

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Detalles Bibliográficos
Autores principales: Welten, Sabine M.J., de Vries, Margreet R., Peters, Erna A.B., Agrawal, Sudhir, Quax, Paul H.A., Nossent, A. Yaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415962/
https://www.ncbi.nlm.nih.gov/pubmed/28624225
http://dx.doi.org/10.1016/j.omtn.2017.03.003