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Assessing the presence of shared genetic architecture between Alzheimer's disease and major depressive disorder using genome-wide association data
Major depressive disorder (MDD) and Alzheimer's disease (AD) are both common in older age and frequently co-occur. Numerous phenotypic studies based on clinical diagnoses suggest that a history of depression increases risk of subsequent AD, although the basis of this relationship is uncertain....
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416691/ https://www.ncbi.nlm.nih.gov/pubmed/28418403 http://dx.doi.org/10.1038/tp.2017.49 |