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The histamine H3 receptor antagonist thioperamide rescues circadian rhythm and memory function in experimental parkinsonism
Parkinson's disease (PD) is a common neurodegenerative disorder, characterized by motor impairment and a wide range of non-motor symptoms, including sleep disorders and cognitive and affective deficits. In this study, we used a mouse model of PD based on 6-hydroxydopamine (6-OHDA) to examine th...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416699/ https://www.ncbi.nlm.nih.gov/pubmed/28398338 http://dx.doi.org/10.1038/tp.2017.58 |