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The histamine H3 receptor antagonist thioperamide rescues circadian rhythm and memory function in experimental parkinsonism

Parkinson's disease (PD) is a common neurodegenerative disorder, characterized by motor impairment and a wide range of non-motor symptoms, including sleep disorders and cognitive and affective deficits. In this study, we used a mouse model of PD based on 6-hydroxydopamine (6-OHDA) to examine th...

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Detalles Bibliográficos
Autores principales: Masini, D, Lopes-Aguiar, C, Bonito-Oliva, A, Papadia, D, Andersson, R, Fisahn, A, Fisone, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416699/
https://www.ncbi.nlm.nih.gov/pubmed/28398338
http://dx.doi.org/10.1038/tp.2017.58