Large-scale interaction effects reveal missing heritability in schizophrenia, bipolar disorder and posttraumatic stress disorder

Genetic susceptibility factors behind psychiatric disorders typically contribute small effects individually. A possible explanation for the missing heritability is that the effects of common variants are not only polygenic but also non-additive, appearing only when interactions within large groups a...

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Detalles Bibliográficos
Autores principales: Woo, H J, Yu, C, Kumar, K, Reifman, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416702/
https://www.ncbi.nlm.nih.gov/pubmed/28398343
http://dx.doi.org/10.1038/tp.2017.61

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416702/
https://www.ncbi.nlm.nih.gov/pubmed/28398343
http://dx.doi.org/10.1038/tp.2017.61

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