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Naltrexone modulates dopamine release following chronic, but not acute amphetamine administration: a translational study

The opioid antagonist naltrexone has been shown to attenuate the subjective effects of amphetamine. However, the mechanisms behind this modulatory effect are currently unknown. We hypothesized that naltrexone would diminish the striatal dopamine release induced by amphetamine, which is considered an...

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Detalles Bibliográficos
Autores principales: Jayaram-Lindström, N, Guterstam, J, Häggkvist, J, Ericson, M, Malmlöf, T, Schilström, B, Halldin, C, Cervenka, S, Saijo, T, Nordström, A-L, Franck, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416714/
https://www.ncbi.nlm.nih.gov/pubmed/28440810
http://dx.doi.org/10.1038/tp.2017.79