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Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2

Aberrant activation of RAS/MAPK signaling is a driver of over one third of all human carcinomas. The homologous transcription factors ETS1 and ETS2 mediate activation of gene expression programs downstream of RAS/MAPK signaling. ETS1 is important for oncogenesis in many tumor types. However, ETS2 ca...

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Detalles Bibliográficos
Autores principales: Plotnik, Joshua P., Hollenhorst, Peter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416753/
https://www.ncbi.nlm.nih.gov/pubmed/28119415
http://dx.doi.org/10.1093/nar/gkx039