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Repair of UV-induced DNA lesions in natural Saccharomyces cerevisiae telomeres is moderated by Sir2 and Sir3, and inhibited by yKu–Sir4 interaction

Ultraviolet light (UV) causes DNA damage that is removed by nucleotide excision repair (NER). UV-induced DNA lesions must be recognized and repaired in nucleosomal DNA, higher order structures of chromatin and within different nuclear sub-compartments. Telomeric DNA is made of short tandem repeats l...

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Detalles Bibliográficos
Autores principales: Guintini, Laetitia, Tremblay, Maxime, Toussaint, Martin, D’Amours, Annie, Wellinger, Ralf E., Wellinger, Raymund J., Conconi, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416773/
https://www.ncbi.nlm.nih.gov/pubmed/28334768
http://dx.doi.org/10.1093/nar/gkx123