Ensemble simulations: folding, unfolding and misfolding of a high-efficiency frameshifting RNA pseudoknot

Massive all-atom molecular dynamics simulations were conducted across a distributed computing network to study the folding, unfolding, misfolding and conformational plasticity of the high-efficiency frameshifting double mutant of the 26 nt potato leaf roll virus RNA pseudoknot. Our robust sampling,...

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Detalles Bibliográficos
Autores principales: Q. Nguyen, Khai K., Gomez, Yessica K., Bakhom, Mona, Radcliffe, Amethyst, La, Phuc, Rochelle, Dakota, Lee, Ji Won, Sorin, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416846/
https://www.ncbi.nlm.nih.gov/pubmed/28115636
http://dx.doi.org/10.1093/nar/gkx012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416846/
https://www.ncbi.nlm.nih.gov/pubmed/28115636
http://dx.doi.org/10.1093/nar/gkx012

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