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Ensemble simulations: folding, unfolding and misfolding of a high-efficiency frameshifting RNA pseudoknot
Massive all-atom molecular dynamics simulations were conducted across a distributed computing network to study the folding, unfolding, misfolding and conformational plasticity of the high-efficiency frameshifting double mutant of the 26 nt potato leaf roll virus RNA pseudoknot. Our robust sampling,...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416846/ https://www.ncbi.nlm.nih.gov/pubmed/28115636 http://dx.doi.org/10.1093/nar/gkx012 |