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The spacer size of I-B CRISPR is modulated by the terminal sequence of the protospacer

Prokaryotes memorize invader information by incorporating alien DNA as spacers into CRISPR arrays. Although the spacer size has been suggested to be predefined by the architecture of the acquisition complex, there is usually an unexpected heterogeneity. Here, we explored the causes of this heterogen...

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Detalles Bibliográficos
Autores principales: Li, Ming, Gong, Luyao, Zhao, Dahe, Zhou, Jian, Xiang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416893/
https://www.ncbi.nlm.nih.gov/pubmed/28379481
http://dx.doi.org/10.1093/nar/gkx229