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Dual-Function Polymeric HPMA Prodrugs for the Delivery of miRNA
[Image: see text] An HPMA-based polymeric prodrug of a CXCR4 antagonist, AMD3465 (P-SS-AMD), was developed as a dual-function carrier of therapeutic miRNA. P-SS-AMD was synthesized by a copolymerization of HPMA with a methacrylamide monomer in which the AMD3465 was attached via a self-immolative dis...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417087/ https://www.ncbi.nlm.nih.gov/pubmed/28134535 http://dx.doi.org/10.1021/acs.molpharmaceut.6b00999 |