Crystal structure of CD27 in complex with a neutralizing noncompeting antibody

CD27 is a T-cell and B-cell co-stimulatory glycoprotein of the tumor necrosis factor (TNF) receptor superfamily that is dependent on the availability of the TNF-like ligand CD70. Therapeutic approaches to treating autoimmune diseases and cancers with antagonistic and agonistic anti-CD27 monoclonal a...

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Detalles Bibliográficos
Autores principales: Teplyakov, Alexey, Obmolova, Galina, Malia, Thomas J., Gilliland, Gary L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2017
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417320/
https://www.ncbi.nlm.nih.gov/pubmed/28471362
http://dx.doi.org/10.1107/S2053230X17005957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417320/
https://www.ncbi.nlm.nih.gov/pubmed/28471362
http://dx.doi.org/10.1107/S2053230X17005957

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