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Tissue-Specific Differentiation of Colonic Macrophages Requires TGFβ Receptor Mediated Signalling

Intestinal macrophages (mϕ) form one of the largest populations of mϕ in the body and are vital for the maintenance of gut homeostasis. They have several unique properties and are derived from local differentiation of classical Ly6C(hi) monocytes, but the factors driving this tissue-specific process...

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Detalles Bibliográficos
Autores principales: Schridde, Anika, Bain, Calum C, Mayer, Johannes U, Montgomery, Jennifer, Pollet, Emeline, Denecke, Bernd, Milling, Simon WF, Jenkins, Stephen J, Dalod, Marc, Henr, Sandrinei, Malissen, Bernard, Pabst, Oliver, Mowat, Allan McI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417360/
https://www.ncbi.nlm.nih.gov/pubmed/28145440
http://dx.doi.org/10.1038/mi.2016.142