Ultra-deep sequencing reveals high prevalence and broad structural diversity of hepatitis B surface antigen mutations in a global population

The diversity of the hepatitis B surface antigen (HBsAg) has a significant impact on the performance of diagnostic screening tests and the clinical outcome of hepatitis B infection. Neutralizing or diagnostic antibodies against the HBsAg are directed towards its highly conserved major hydrophilic re...

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Detalles Bibliográficos
Autores principales: Gencay, Mikael, Hübner, Kirsten, Gohl, Peter, Seffner, Anja, Weizenegger, Michael, Neofytos, Dionysios, Batrla, Richard, Woeste, Andreas, Kim, Hyon-suk, Westergaard, Gaston, Reinsch, Christine, Brill, Eva, Thu Thuy, Pham Thi, Hoang, Bui Huu, Sonderup, Mark, Spearman, C. Wendy, Pabinger, Stephan, Gautier, Jérémie, Brancaccio, Giuseppina, Fasano, Massimo, Santantonio, Teresa, Gaeta, Giovanni B., Nauck, Markus, Kaminski, Wolfgang E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417417/
https://www.ncbi.nlm.nih.gov/pubmed/28472040
http://dx.doi.org/10.1371/journal.pone.0172101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417417/
https://www.ncbi.nlm.nih.gov/pubmed/28472040
http://dx.doi.org/10.1371/journal.pone.0172101

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