Cargando…
Both MAPK and STAT3 signal transduction pathways are necessary for IL-6-dependent hepatic stellate cells activation
BACKGROUND: During liver injury, hepatic stellate cells (HSCs) can undergo activation and transform into alpha-smooth muscle actin (αSMA)-expressing contractile myofibroblast-like cells, leading to deposition of excessive scar matrix. We have recently demonstrated that depletion of adenosine deamina...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417441/ https://www.ncbi.nlm.nih.gov/pubmed/28472150 http://dx.doi.org/10.1371/journal.pone.0176173 |