Both MAPK and STAT3 signal transduction pathways are necessary for IL-6-dependent hepatic stellate cells activation

BACKGROUND: During liver injury, hepatic stellate cells (HSCs) can undergo activation and transform into alpha-smooth muscle actin (αSMA)-expressing contractile myofibroblast-like cells, leading to deposition of excessive scar matrix. We have recently demonstrated that depletion of adenosine deamina...

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Detalles Bibliográficos
Autores principales: Kagan, Polina, Sultan, Maya, Tachlytski, Irina, Safran, Michal, Ben-Ari, Ziv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417441/
https://www.ncbi.nlm.nih.gov/pubmed/28472150
http://dx.doi.org/10.1371/journal.pone.0176173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417441/
https://www.ncbi.nlm.nih.gov/pubmed/28472150
http://dx.doi.org/10.1371/journal.pone.0176173

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